
With over 20 years of expertise in flow chemistry and a technology trusted by hundreds of chemists around the world, UK-based instrument manufacturer Vapourtec is changing the peptide synthesizer market. Already adopted by several pharmaceutical and biotechnology companies, as well as academic institutes, Vapourtec’s peptide synthesis product portfolio is based on Fast Flow Solid Phase Peptide Synthesis (FF-SPPS). So why should anyone move their peptide synthesis to FF-SPPS?
Eliminating randomness, increasing crude purity
One of the key characteristics that differentiates FF-SPPS from a batch synthesis, is the arrangement of the solid media. In batch, solid media is stirred in a vessel, continuously mixing. Reagents are then added to the vessel for the reaction to occur. The coupling process is random, and with every coupling the impurity profile increases to give a normal distribution of deletions.
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