2025

Advances in Polymeric based Drug Delivery Systems

by cyb2025

JULIETTE MARTIN
Scientific Communication Manager at SEQENS Innovative BU – CDMO

ABSTRACT

In this article, we wish to highlight the evolution of drug delivery technologies alongside generations of therapeutics, from small molecules to proteins and peptides, to nucleic acids and, most recently, to live-cell therapies.
We will first introduce the context and therapeutic applications of polymeric based drug delivery systems. We will then describe the advances of delivery approaches, with a focus on biodegradable and bio-absorbable polymers, bio-related copolymers and dendrimers.
We will illustrate with two case studies based on water-soluble synthetic polymers that have emerged as essential tools for many biomedical applications. Backed with our experience and expertise in polymer-based chemistry and manufacturing, these polymers are poised to further advance in the realm of biomedicine.

Introduction

 

Drug delivery technologies have enabled the development of many pharmaceutical products by enhancing the delivery of a therapeutic to its target site, minimizing off-target accumulation and facilitating patient compliance.
In recent decades, the fusion of polymer science and biomedical research has led to groundbreaking advancements, opening up numerous opportunities to enhance therapeutic efficiency. Drug delivery technologies have been expanded beyond small molecules to include nucleic acids, peptides, proteins and antibodies.

 

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