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The third molecule which we are going to present here at “API of the Month” is pacritinib, a selective oral Janus kinase inhibitor (JAK2) used for the treatment of adults with intermediate or high-risk myelofibrosis with a platelet count below 50 × 109/L. Pacritinib sold under the brand name Vonjo (CTI BioPharma) was approved on 28th of February 2022 with an oral, 200 mg dose, twice daily (1, 2).
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